|
KMID : 0043319950180030206
|
|
Archives of Pharmacal Research
1995 Volume.18 No. 3 p.206 ~ p.212
|
|
|
Synthesis and Biological Activity of Indazole-Derived HMG-CoA Reductase Inhibitors
|
|
Kim Jin-Il
Jahng Yurng-Dong
|
|
|
Abstract
|
|
|
|
New hypolipaemic agents, in which substituted indazole nucleus is connected to tetrahydro-4-hydroxy-2H-pyran-2-one by a two-carbon bridge, were designed and synthesized to show significant inhibitory activity against microsomal HMG-CoA reductase in rat liver.
|
|
|
KEYWORD
|
|
|
Hypolipaemic Agent, HMG-CoA reductase inhibitor, Substituted indazoles
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|